Understanding Recurrence in Breast Ductal Carcinoma in Situ

Phylogenetic analysis of paired breast carcinomas identifies genetic events associated with clonal recurrence and invasive progression

T Kader, M Zethoven, S Mahale, H Saunders, L Tjoeka, R Lehmann, MW Jayawardana, JM Pang, D Lesche, N Rajan, T Semple, JEA Lee, R Lupat, DJ Byrne, S Hughes, H Nguyen, S Lai, M Pechlivanis, O Craig, L Devereux

2026-01-01

Development of ipsilateral breast carcinoma following a diagnosis of breast ductal carcinoma in situ (DCIS) has been assumed to re..

Identifying recurrences and metastasis after ductal carcinoma in situ (DCIS) of the breast

RI Udayasiri, T Luo, KL Gorringe, SB Fox

2023-01-01

Ductal carcinoma in situ (DCIS) of the breast is a non-invasive tumour that has the potential to progress to invasive ductal carci..

Evaluating statistical approaches to define clonal origin of tumours using bulk DNA sequencing: context is everything

T Kader, M Zethoven, KL Gorringe

2022-12-01

Clonal analysis of tumour sequencing data enables the evaluation of the relationship of histologically distinct synchronous lesion..

The prognostic significance of immune microenvironment in breast ductal carcinoma in situ

MS Toss, A Abidi, D Lesche, C Joseph, S Mahale, H Saunders, T Kader, IM Miligy, AR Green, KL Gorringe, EA Rakha

2020-05-12

Background: The role of different subtypes of tumour infiltrating lymphocytes (TILs) in breast ductal carcinoma in situ (DCIS) is ..